FOXBOX呼(hu)吸代謝技術(shu)助力(li)右(you)美(mei)托咪定(ding)治(zhi)療(liao)COVID19重(zhong)癥患者研(yan)究

據SSI呼(hu)吸代謝技術(shu)2026年01月(yue)10日最新參(can)考(kao)信息，鎮靜劑(ji)右(you)美(mei)托咪定(ding)可(ke)能有(you)助於治(zhi)療(liao)重(zhong)癥監(jian)護中(zhong)的(de)COVID19患者——但(dan)它如何(he)影響(xiang)呼(hu)吸和血壓(ya)？

右(you)美(mei)托咪定(ding)可(ke)維(wei)持壹定(ding)程(cheng)度的(de)鎮靜狀(zhuang)態，有(you)利於降低(di)機(ji)體(ti)的(de)氧耗(hao)率，改(gai)善(shan)氧合(he)。來(lai)自(zi)日(ri)本(ben)牙(ya)科大學的(de)科學家采(cai)用Foxbox呼(hu)吸代謝技術(shu)構(gou)建(jian)了如下(xia)圖(tu)所(suo)示(shi)的(de)鎮靜大鼠(shu)呼(hu)吸與血壓(ya)測定(ding)裝(zhuang)置(zhi)，進行右(you)美(mei)托咪定(ding)對自(zi)主呼(hu)吸成年大鼠(shu)心(xin)肺調(tiao)節影響(xiang)研(yan)究。

相關(guan)研究成果(guo)見2022年1月(yue)14日PLOS ONE在(zai)線論(lun)文“Effect of dexmedetomidine on cardiorespiratory regulation in spontaneously breathing adult rats"。

參考(kao)資料(liao)

1.Zhou L, Gu W, Kui F, et al. The mechanism and candidate compounds of aged citrus peel (chenpi) preventing chronic obstructive pulmonary disease and its progression to lung cancer. Food & Nutrition Research. 2021 ;65. DOI: 10.29219/fnr.v65.7526. 

2.Wearing, O.H., Ivy, C.M., Gutiérrez-Pinto, N. et al. The adaptive benefit of evolved increases in hemoglobin-O2 affinity is contingent on tissue O2 diffusing capacity in high-altitude deer mice. BMC Biol 19, 128 (2021).

3.Catherine M.Ivy,Haley Prest,Claire M.West,and Graham R.Scott. Distinct Mechanisms Underlie Developmental Plasticity and Adult Acclimation of Thermogenic Capacity in High-Altitude Deer Mice. Front Physiol. 2021;12:718163. 11.doi:10.3389/fphys.2021.718163.